CJC-1295 (Without DAC)
Synthetic 30-amino acid analogue of GHRH(1-29). Mass-spec certified, lyophilized, research-grade.
Frequently researched together
Technical specifications
CJC-1295 (with DAC) is a synthetic peptide analogue of Growth Hormone-Releasing Hormone (GHRH), a 44-amino-acid hypothalamic peptide that stimulates pituitary somatotroph cells in vivo. The CJC-1295 sequence corresponds to GHRH(1-29) with substitutions to improve protease resistance, conjugated to a Drug Affinity Complex (DAC) moiety that covalently binds to serum albumin after reconstitution, prolonging circulating half-life in pharmacokinetic model studies. It is used in research settings to study the GHRH–GH axis signaling dynamics and receptor binding kinetics.
- Analogue of GHRH(1-29) — the biologically active fragment of the 44-amino-acid hypothalamic hormone
- DAC moiety enables covalent binding to serum albumin for extended half-life in PK studies
- Amino acid substitutions at positions 2, 8, 15, and 27 increase resistance to dipeptidyl peptidase IV (DPP-IV)
- Endogenous GHRH is secreted in pulsatile fashion from the arcuate nucleus of the hypothalamus
- Lyophilized; reconstituted with bacteriostatic water for in vitro or animal model studies
- Strictly for in vitro and animal model research — not for human or veterinary use
Peer-reviewed research
All products sold by Next Level Research LLC are intended for laboratory and research use only. Not for human or animal consumption. Not a drug, food, or cosmetic. No therapeutic claims are made.